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Amino acid sequences were aligned with their respective prototypes in s to penicillin, tetracycline, ciprofloxacin or spectinomycin for the two groups were within a 2-fold dilution (data not shown). There was no significant difference ( isolates carried A39T or G45D (63.2%, 12/19) or H105Y (36.8%, 7/19) single mutations (Table 3).
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